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Irwin 2013: Different Fates of Alzheimer’s Disease Amyloid-beta Fibrils Remodeled by Biocompatible Small Molecules

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Irwin, Wong, Kwon. Biomacromolecules. 14(1): 264- 274. Amyloid fibrils such as those found in Alzheimer’s disease are thermodynamically very stable, but there is evidence that small molecules like food dyes can remodel them safely. The authors performed a remodeling trial … Continue reading

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Al-Shabib 2019: Allura Red Rapidly Induces Amyloid-Like Fibril Formation in Hen Egg White Lysozyme at Physiological pH

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International Journal of Biological Macromolecules. 127: 297-305 Red 40, with hen egg white lysozyme (HEWL), forms amyloid-like aggregates. (A lysozyme is an enzyme in human tears and egg white.) The amyloid fibril formation can be observed by an electron microscope, … Continue reading

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Kwon 2022: Chronic Exposure to Synthetic Food Colorant Allura Red AC Promotes Susceptibility to Experimental Colitis via Intestinal Serotonin in Mice

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Nature Communications, December 2022, 13 : 7617 FD&C Red #40 is also commonly called “Allura Red” as it is referred to in this paper.  It is abbreviated as “AR” in this study and in the picture at right.  As you … Continue reading

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Pham 2021: Using High-Throughput Screening to Evaluate Perturbations Potentially Linked to Neurobehavioral Outcomes: A Case Study Using Publicly Available Tools on FDA Batch-Certified Synthetic Food Dyes

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Chemical Research in Toxicology, 2021, 34(11), 2319-2330. QUOTE:  “There is growing evidence from human and animal studies indicating an association between exposure to synthetic food dyes and adverse neurobehavioral outcomes in children.” The authors developed  a way to evaluate the … Continue reading

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Abril-Gil 2015: Development and Characterization of an Effective Food Allergy Model in Brown Norway Rats

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PLoS ONE,  10(4): e0126314. Food allergies in children have been increasing in recent decades, so there is a need to create an allergic animal model in order to study this problem.   This is normally accomplished by giving the rats a … Continue reading

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Will your doctor be allowed to help you?

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By Jane Hersey, author of Why Can’t My Child Behave? Dr. Ben F. Feingold’s dietary protocol for treating the growing number of children with behavior problems was simple, safe, and affordable. Although he received harsh criticism from members of the … Continue reading

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WHO “Solidarity” & UK “Recovery” clinical trials of Hydroxychloroquine using potentially fatal doses, according to WHO consultant

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Dr. Meryl Nass describes two large studies on HCQ, using very high and potentially fatal doses.  The intent, apparently, was to prove this drug to be dangerous in spite of a half-century history of safe use at appropriate doses. Based … Continue reading

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Cismaru 2021: COVID-19 and antimalarials. Have we been doing it wrong all along?

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European Journal of Pharmacology, Jan 15;891:173694 The authors recommend that instead of using Hydroxychloroquine (HCQ) together with the macrolide antibiotic Azithromycin, doctors should first use HCQ and follow this with the addition of Azithromycin. The picture at right describes the … Continue reading

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Pestana 2010: Safety of ingestion of yellow tartrazine by double-blind placebo contgrolled challenge in 26 atopic adults.

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Allergologie et Immunopathologia (Madrid). 2010 May-June; 38 (3): 142-6. In this study, styling itself as a “gold standard, double-blind placebo controlled, crossed-over challenge,” 26 adults with atopy (skin or asthma allergy) were tested for tartrazine (Yellow 5) sensitivity and had … Continue reading

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Dixit 2013: All India survey for analyses of colors in sweets and savories: Exposure risk in Indian population

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Journal of Food Science. 2013 April; 78(4): T642-7 This is the first national study on food additive use in India, collecting data on “sweets and savories.” Their dye extraction and identification technique (using pure wool strands) is described, as is … Continue reading

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Vally 2000: Alcoholic drinks: important triggers for asthma

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Journal of Allergy and Clinical Immunology, 2000 Mar;105(3):462-7 In this study, a questionnaire was filled out by 366 adult asthma patients.  Over 33% of them said that their asthma had been triggered by alcohol at least twice, with wine reported … Continue reading

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Neuman 1978: The danger of “yellow dyes” (tartrazine) to allergic subjects

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Clinical Allergy. 1978 Jan;8(1): 65-8. In an Israeli hospital, Neuman et al tested the effect of 50 mg of tartrazine (Yellow 5) on 97 patients with a variety of allergic disorders and 25 with non-allergic rhinitis.  First, all patients were … Continue reading

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Ceyhan 2013: Effects of maternally exposed coloring food additives on receptor expressions related to learning and memory in rats.

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Food and Chemical Toxicology, 2013 Jun;56:145-8. In a study of rats, the authors found that exposing them to food dyes before birth changed the expression of certain receptors when they grew up.  The particular receptors (NMDAR and nAChR) are involved … Continue reading

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Doguc 2013: Effects of maternally exposed colouring food additives on cognitive performance in rats

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Toxicology and Industrial Health, 2013. Aug; 29(7): 616-23.  Doguc, Ceyhan, Ozturk, Gultekin In this study, pregnant rats were given the ADI (Acceptable Daily Intake) amounts of the following food dyes by mouth, continuing to do so after the babies were … Continue reading

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Bateman 2004: The effects of a double blind, placebo controlled, artificial food colourings and benzoate preservative challenge on hyperactivity in a general population sample of preschool children

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Archives of Disease in Childhood. 2004 Jun;89(6):506-11. The authors put 277  3-year-old children from the general population on a diet without artificial food dyes or benzoate preservatives for a week, and then challenged them at various times with a drink … Continue reading

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Bennett 1998 The Shipley Project: Treating Food Allergy to Prevent Criminal Behaviour in Community Settings

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Journal of Nutritional & Environmental Medicine , Vol.8, No.1, Mar.1998, pp.77-83 All 9 children with disruptive and/or criminal behavior in this study were found to have a number of food allergies or intolerances and mineral imbalances, particularly zinc. Three also … Continue reading

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Bennett 1997: The Health of Criminals Related to Behaviour, Food, Allergy and Nutrition: A Controlled Study of 100 Persistent Young Offenders

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Journal of Nutritional & Environmental Medicine, Vol.7, No.4 Dec 1997 pp.359-366 About 75% of persistent young offenders have behaviors linked to food sensitivity and nutrition problems; only 18% of young non-offenders have such problems. MedLine || Full Text || Get Password

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Kaplan 1989: Overall Nutrient Intake of Preschool Hyperactive and Normal Boys

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Journal of Abnormal Child Psychology, April 1989, Vol. 17(2), pp.127-32. Kaplan compared food diaries of children with and without ADHD and concluded that it was idiosyncratic sensitivities to components in the diet rather than a different overall diet. MedLine || … Continue reading

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Egger 1983: Is migraine food allergy? A double-blind controlled trial of oligoantigenic diet treatment

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Lancet, 1983. Oct 15;2(8355):865-9 93% of 88 children with severe frequent migraine recovered on an oligoantigenic (few foods) diet.  40 of them were challenged with various foods in a double-blind test, establishing that it was the diet that had helped.  … Continue reading

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Goyette 1978: Effects of artificial colors on hyperkinetic children: a double-blind challenge study

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Psychopharmacology Bulletin, 1978. April;  14(2):39-40 Goyette performed two studies: Experiment One:  16 children were put on the diet and were much improved according to both parents and teachers.  Then they were challenged with two cookies per day (with or without … Continue reading

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Levy 1978: Hyperkinesis and diet: a double-blind crossover trial with a tartrazine challenge

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Medical Journal of Australia, 1978. Jan 28;1(2):61-4 In this double-blind study of 22 hyperactive children, Levy put them on an elimination diet for four weeks and then challenged them with Yellow 5.  She reported that their improvement in the first … Continue reading

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Salzman 1976: Allergy testing, psychological assessment and dietary treatment of the hyperactive child syndrome

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Medical Journal of Australia 1976 Aug 14;2(7):248-51 Thirty-one children with behavioural problems and learning difficulties were allergy tested … 15 of them were given the Feingold diet (then called the KP Diet).  Ninety-three per cent (93%) responded with improved behaviour … Continue reading

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Cherry 2019: The 112-year odyssey of Pertussis and Pertussis vaccines — mistakes made and implications for the future

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Journal of the Pediatric Infectious Diseases Society, Sep 25;8(4):334-341 The author discusses the connection of the Pertussis vaccine, linked epitope suppression, and how it is similar to something called the “original antigenic sin” in influenza.    Basically, once someone is vaccinated, … Continue reading

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Warfel 2014: Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model

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Warfel, Zimmerman, Merkel, Proceedings of the National Academy of Sciences of the USA FINDINGS:  The vaccine induces a response mismatched to natural infection. The vaccine fails to prevent colonization or transmission. The antibodies produced by the vaccine do not mitigate  … Continue reading

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Trasande 2018: Food additives and child health

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Trasande, Shaffer, Sathyanarayana. Pediatrics. 142(2) The purpose of this paper is to review “emerging child health concerns related to the use of colorings, flavorings, and chemicals deliberately added to food during processing … as well as substances in food contact … Continue reading

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Olas 2021: The effects of natural and synthetic blue dyes on human health: A review of current knowledge and therapeutic perspectives

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Olas, Bialecki, Urbanska, & Brys:  Advances in Nutrition, Dec 1;12(6):2301-2311. The only approved natural sources of blue coloring used in foods, so far, are grape color extract and grape skin extract. Both of these contain anthocyanin grape pigments This paper … Continue reading

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Europe – the next Islamic Caliphate?

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Please post on Facebook or X, or any other social media of your choice, so  as many as possible can read it.  If he’s right, we need to know. This is a speech  by Geert Wilders, a member of the … Continue reading

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Colnot 2022: Chronic maternal exposure to titanium dioxide nanoparticles alters breathing in newborn offspring

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Particle and Fibre Toxicology, 19:57.  Colnot, Cardoit, Cabirol, … Morin Particles of titanium dioxide (TiO2) are one of the nanomaterials most frequently found in everyday consumer products, including foods.   TiO2 has  long been considered a safe food coloring and … Continue reading

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Zhang 2023: The synthetic food dye, Red 40, causes DNA damage, causes colonic inflammation, and impacts the microbiome in mice

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Zhang, Chumanevich, Nguyen, … Hofseth. Toxocology Reports. (11) 221-232 We  have long suggested that Red 40 (Allura Red) plays a role in behavioral problems, but here is another angle: it appears likely that Red 40 is also involved in the … Continue reading

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Hughes 1988: A tribute to toilet paper

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Reviews of Infectious Diseases, Vol. 10, No. 1., 1988.  From the Divisions of Infectious Disease, St. Jude Children’s Research Hospital, Memphis, TN The author was surprised to find that there has actually been no research on the benefits of toilet … Continue reading

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Zand 2023: Tartrazine modifies the activity of DNMT and HDAC genes — is this a link between cancer and neurological disorders?

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Nutrients, 2023, June 28, 15(13) 2946. This study is intended to determine the long-term (3o and 90 days) exposure to tartrazine (Yellow 5) on humanized (NMRI) mice. The amount used was the equivalent of the human acceptable daily intake (ADI). … Continue reading

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Pfizer employees didn’t get the same vaccine as the rest of us.

BOMBSHELL: Pfizer employees were given a *special batch*… different from what was forced into the general population 🚨🚨🚨 pic.twitter.com/CDww6wxFif — Pelham (@Resist_05) August 4, 2023 So … what did they get?  Considering that it is now known that 1/3 of … Continue reading

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Wopara 2021a: Involvement of Striatal Oxido-Inflammatory, Nitrosative and Decreased Cholinergic Activity in Neurobehavioral Alteration in Adult Rat Model with oral Co-Exposure to Erythrosine and Tartrazine

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Wopara, Adebayo, Umoren, … Wodo.  Heliyon, 7. e08454. e-collection, 21 Nov. Don’t let the complex nature of the picture below (or the title above) distress you — what all the fancy words mean is that this study shows that the … Continue reading

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Lamport 2016: Concord Grape Juice, Cognitive Function, and Driving Performance: A 12-wk, Placebo-Controlled, Randomized Crossover Trial in Mothers of Preteen Children

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Lamport, Lawton, Merat …  Dye.  American Journal of Clinical Nutrition. 103: 775-783. The intent of this study, funded by Welch Foods, was to show that grape juice improves driving ability in stressed people (moms of teens). The authors concluded that … Continue reading

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Kobylewski 2012: Toxicology of food dyes

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Kobylewski & Jacobson.  International Journal of Occupational and Environmental Health. 18(3): 220-246. This review of the toxicology of food dyes finds that all nine of the currently approved dyes in the US have health concerns, including cancer, contamination with benzidine … Continue reading

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Karimi 2023: Post-Weaning Exposure to Sunset Yellow FCF Induces Changes in Testicular Tight and Gap Junctions in Rats: Protective Effects of Coenzyme Q10

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Reproductive Sciences. 2023 Apr 18. doi: 10.1007/s43032-023-01240-w. Online ahead of print. Karimi, Khodabandeh, Nazari, Dara, Masjedi, Momeni-Moghaddam This study investigates the toxic effects of the food dye Yellow #6 (Sunset Yellow) on rat testicles, and the protective effects of CoQ10. … Continue reading

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Monteiro 2023: Dietary Exposure to Food Azo-Colours in a Sample of Pre-School Children from Southern Brazil

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Food Additives & Contaminants,  Part A Chemistry, Analysis, Control, Exposure & Risk Assessment.  2023 Apr 26;1-12. doi: 10.1080/19440049.2023.2203778. Online ahead of print In Guaratuba-Parana, Brazil, the diet of 323 preschool children aged 2 to 5 years were studied for three … Continue reading

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Kim 2018: Associations between Attention-Deficit/Hyperactivity Disorder Symptoms and Dietary Habits in Elementary School Children

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Kim et al.  Appetite. 127: 274-279. More than 16,000 parents in Korea responded to the Korean version of the ADHD rating scale and also to a food questionnaire. The study found that ADHD symptoms are positively associated with higher consumption … Continue reading

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Institute of Food Technologists 1986: Food Colors.

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Food Technology.  49-56. This is a scientific status summary by the Expert Panel on Food Safety & Nutrition, based on the Survey of Industry on the Use of Food Additives, by the National Academy of Sciences, from 1977. The 1977 … Continue reading

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Ferreira 2016: Brilliant Blue Dyes in Daily Food: How Could Purinergic System be Affected?

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Ferreira, Faria, da Silva Ferreira, Soares-Bezerra.  International Journal of Food Science. 2016:7548498 Ferreira reviewed what was known about the medical uses of Blue 1. The purinergic system is widespread throughout the brain, nervous system and every other system in the … Continue reading

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Ferrazoli 2017: Brilliant Blue G, But Not Fenofibrate, Treatment Reverts Hemiparkinsonian Behavior and Restores Dopamine Levels in an Animal Model of Parkinson’s Disease

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Ferrazoli, de Souza, Nascimento, Oliveira-Giacomelli, Schwindt, Britto, Ulrich.  Cell Transplantation. 26: 669-677. This paper describes an effect of Blue 1 ofpotential medical benefit in Parkinson’sdisease.   Basically, it can be used to suppress a receptor that is over-active and causing damage … Continue reading

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Eagle 2012: SULT1A Inhibition and How a Migraine Stops

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Eagle.  Headache. 52(8):  1321. This paper describes how SULT1A enzymes affect dopamine, a neurotransmitter. Yellow 5 (Tartrazine) is one of the items that can inhibit SULT1A (Note: SULT1A is called PST in some studies). Elevated dopamine is generally blamed for … Continue reading

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Eagle 2012: Toxicological Effects of Red Wine, Orange Juice, and Other Dietary SULT1A Inhibitors via Excess Catecholamines

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Eagle.  Food and Chemical Toxicology. 40: 2243-2249. This is an overview of how certain compounds affect the enzymes called phenolsulfotransferase (also called PST or SULT1A), and how enzyme inhibition enzyme causes problems such as migraines, heart arrhythmias, or increased blood … Continue reading

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Cruz 2006: Do Food or Additives Cause Behavior Disorders?

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Cruz, Bahna. Pediatric Annals. 35(10): 744-5, 748-754. This was written as advice to doctors.  It included a review of studies “both in support and against the possibility of such a relationship.” NOTE:  The studies cited — in 2006 — were … Continue reading

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Braganza 2006: Nutritional Interventions: Part Two. When Parents Ask About Diet Therapy for ADHD.

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Braganza, Galvez, Ozuah.  Contemporary Pediatrics. 23(5): 47-49. This paper’s stated purpose was to advise doctors on how to respond to parents asking about diet therapy for ADHD – in particular, the Feingold diet. To support their opinion, Braganza et al … Continue reading

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Bhatt 2018: Tartrazine Induced Neurobiochemical Alterations in Rat Brain Sub- Regions.

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Bhatt, Vyas, Singh, John, Soni.   Food and Chemical Toxicology. 113:322-327.Rats were given the ADI (acceptable daily intake) amount of Tartrazine (Yellow 5). Their body weight was lower. The brain protein levels in all their brain sub-regions decreased. Lipid peroxide … Continue reading

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Bamforth 1993: Common Food Additives are Potent Inhibitors of Human Liver 17α-Ethinyloestradiol and Dopamine Sulphotransferases

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Bamforth, Jones, Roberts, Coughtrie. Biochemical  Pharmacology. 46(10): 1713-1720. Detoxification enzymes provide the means for inactivation, transport and excretion of the xenobiotics including food dyes. Sulfate conjugation is one of the important methods of handling these compounds. Not only are the … Continue reading

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Kaplan 1989: Dietary replacement in preschool-aged hyperactive boys

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Pediatrics.  Jan;83(1):7-17 The authors tested a number of children using what could be called a “stage two Feingold Diet.” The diet used, in other words, eliminated food dyes and several other additives, but did not eliminate salicylate-containing foods such as … Continue reading

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Apolloni 2014: Spinal Cord Pathology is Ameliorated by P2X7 Antagonism in a SOD1-Mutant Mouse Model of Amyotrophic Lateral Sclerosis

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Disease Models and Mechanisms. 7(9): 1101-1109. This paper describes a neurological effect of Blue 1 that may be of medical benefit in treating spinal cord pathology in amyotrophic lateral sclerosis (ALS). The receptor P2X7 is involved in the central nervous … Continue reading

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Anderson 1983: Relative Refractory Period as a Measure of Peripheral Nerve Neurotoxicity

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Toxicology and Applied Pharmacology. 71: 391-397. NOTE:  This is not actually a study of Red 3. Rather, the dye, Red 3, is to help develop this testing method, because it is a known excitatory neurotoxin. The relative refractory period is … Continue reading

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Adams 1981: Lack of behavioral effects from Feingold Diet violations

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Perceptual and Motor Skills, 52: 307-313. (FDA study) NOTE:  The Conners’ scores for the children when they were ON the diet were not given, but it is assumed the children had actually responded to the diet before being tested on … Continue reading

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Fauci 2023: Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses

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Cell Host & Microbe, 31, January 11, 2023, pg. 146-157 In spite of the fact that Dr. Fauci has retired as spokesman for the nation about Covid and other diseases, his position listed in this paper is “Office of the … Continue reading

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Why School Lunch Matters to You

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by Jane Hersey Regardless of whether or not you have a child in public school, the food served there has a direct impact on your life. The cost of educating children with learning or behavior problems. The biggest budget item … Continue reading

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Alemany 2021: Prenatal and postnatal exposure to acetaminophen in relation to autism spectrum and attention-deficit and hyperactivity symptoms in childhood: Meta-analysis in six European population-based cohorts

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European Journal of Epidemiology, 2021 Oct;36(10):993-1004 When babies are given their first vaccines, parents are usually advised to give them Tylenol to prevent and/or treat fevers that frequently follow a vaccination.  When moms-to-be are urged to get flu shots and/or … Continue reading

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Updated Science Library

I just wanted to let you all know that the Library has been updated to a PDF page you can download.  It is currently over 500 pages long and includes 3,544 studies at this time, so you may not want … Continue reading

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Feingold Successes

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Feingold Successes Do you have a child with serious problems, and have you been unable to find any real solutions? Like many of us, you may have consulted numerous professionals and received nothing more than a label or a prescription. … Continue reading

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Benn 2019: Lessons Learned from the Testing of Neonatal Vitamin A Supplementation

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This is a review of 12 studies testing the effect of neonatal Vitamin A supplementation.   Two possible theories are considered:  (A) giving this vitamin to babies will prevent Vitamin A deficiency, and (B) giving this vitamin interacts with the DTP … Continue reading

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Inside the Capitol Hill Covid Forum

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If you value your health, don’t miss this short video where doctors and researchers share what they are finding with you in this Hearing with Senator Ron Johnson. In  Senate hearings, all presentations are generally recorded and shared with all … Continue reading

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Sambu 2022: Toxicological and teratogenic effect of various food additives: An updated review

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BioMed Research International, vol. 2022 (6829409). This is a review of some of the chemicals added to foods to improve shelf-life, color or taste, from the point of view of safety of the newborn.   The authors point out that … Continue reading

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Patel 2022: The safety of pediatric use of paracetamol (acetaminophen): A narrative review of direct and indirect evidence

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Minerva Pediatrics, 2022. July 13 DOI: 10.23736/S2724-52765.22.06932-4 Use of Tylenol (paracetamol or acetaminophen) during pregnancy and early childhood has been considered safe since the 1970s.  Parents are urged to use it routinely after vaccination to prevent or control fever. It … Continue reading

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