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Trasande, Shaffer, Sathyanarayana. Pediatrics. 142(2) The purpose of this paper is to review “emerging child health concerns related to the use of colorings, flavorings, and chemicals deliberately added to food during processing … as well as substances in food contact … Continue reading
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Kobylewski & Jacobson. International Journal of Occupational and Environmental Health. 18(3): 220-246. This review of the toxicology of food dyes finds that all nine of the currently approved dyes in the US have health concerns, including cancer, contamination with benzidine … Continue reading
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Ferreira, Faria, da Silva Ferreira, Soares-Bezerra. International Journal of Food Science. 2016:7548498 Ferreira reviewed what was known about the medical uses of Blue 1. The purinergic system is widespread throughout the brain, nervous system and every other system in the … Continue reading
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Faraone, Antshel. Child & Adolescent Psychiatric Clinics of North America. 23(4): 965-72 This paper reviews an evidence-based approach to help doctors explain to parents the relative benefits of nonpharmacologic treatments for ADHD. Food dye exclusion is given a “4” in … Continue reading
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Journal of Antimicrobial Chemotherapy, 2021 Aug 12;76(9):2415-2418 Several drug treatment trials were reviewed in this paper, including the use of Hydroxychloroquine + Azithromycin, Hydroxychloroquine alone, IL-6 Inhibitors, Corticosteroids, Convalescent Plasma, Remdesivir, and “others” including five antiretroviral drugs and two anti-influenza … Continue reading
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Critical Reviews in Food Science and Nutrition. Feb 11;57(3):524-548. In addition to the problem of illegal and carcinogenic food dyes being added to foods — and the ongoing need to detect them — there is growing concern about the safety … Continue reading
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Journal of Child Healthcare. Mar;22(1):68-83 Ludlow and Rogers want to write a review of existing studies, but actually they are stuck with anecdotal reports because so little research has been done in this area. As they say, however, “anecdotal reports … Continue reading
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Nutrients. May 10;10(5). pii: E591 Some of the many substances found in foods are neurotransmitters (NT), including acetylcholine, glutamate, GABA, dopamine, serotonin and histamine. Not only are these neurotransmitters part of the food itself, but they may be added or … Continue reading
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Integrative Food, Nutrition and Metabolism, 2018, 5(4): 1-2 This editorial explores possible nutritional reasons for the huge difference between the United States and the United Kingdom in numbers of children diagnosed with ADHD or autism. After two separate studies in … Continue reading
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Pharmacotherapy. 2017 May;37 (5): 607-610. Albuterol in bottles used for multiple dosing contains benzalkonium chloride (BAC) as a preservative. The authors say that many pediatric hospitals use this kind of albuterol when preparing solutions for continuous nebulized albuterol for asthma … Continue reading
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Scientific Reports, 2018 Jan 15;8(1):788. 17 studies on iron and ADHD were analyzed by Tseng et al in Taiwan. Iron does more than prevent anemia; besides helping in homeostatis of the hemoglobin (red blood cell) structure, iron is important to the … Continue reading
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Although this speech was given in 1978, it could equally apply today. Tragically, his warning went unheeded, and nothing has changed. Ladies and Gentlemen: I am pleased to be with you today to discuss the importance of the School Food … Continue reading
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Nutritional Neuroscience, 2017 Feb 15:1-11. This is a review of studies linking neuro-physiological symptoms to aspartame usage which concludes that aspartame may be responsible for adverse neurobehavioral health outcomes. QUOTE: “Aspartame consumption needs to be approached with caution due to … Continue reading
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Autism. 2014, July; 18(5): 538-44. This is the first report comparing the profiles of children labelled PDA to those in other groups with behavioral overlap. For example, children with conduct problems are strongly motivated by rewards; for PDA, however, rewards … Continue reading
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Journal of Child Psychology and Psychiatry. 2014 July; 55(7):769-70 Beginning with a comment on “PDA” as sometimes used to mean “Public Display of Affection,” Gillberg says that in his own 40 years of clinical experience, PDA/EDA is not at all … Continue reading
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American Journal of Epidemiology, 2016 Aug 1; 184(3):227-32 Giving pregnant women the flu shot is expected not only to prevent the flu in both mothers and newborns, but also to prevent adverse pregnancy outcomes such as preterm birth. According to … Continue reading
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European Child & Adolescent Psychiatry. Sep;26(9): 1067-1079 In her review of the research, Dr. Ly discusses the use of elimination diets for ADHD and autism from the point of view of the interaction of the metabolic, immune, endocrine, and neural … Continue reading
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The Journal of Clinical Psychiatry. 2016 Oct;77(10): e1342-e1347 Drugs used for bipolar disorder often work by down-regulating the brain metabolism of a long-chain omega-6 (or n-6) essential fatty acid called arichidonic acid (AA). The shorter-chain omega-6 (or n-6) essential fatty … Continue reading
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Acta Otorhinolaryngologica Belgica. 1995;49(3): 235-50. In this review of aspirin-sensitive rhinosinusitis, it is described as a non-allergic, non-infectious perennial eosinophilic rhinitis starting in middle age and rarely seen in children. It may also been seen in atopic patients who have … Continue reading
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Journal of Attention Disorders, Vol. 3(1): 30-48 (1999) This review of “alternative” treatments was undertaken for the National Institute of Health (NIH) 1998 Consensus Development Conference on ADHD. 23 treatments were identified. Some were considered effective or possibly effective for … Continue reading
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Journal of the American Academy of Child and Adolescent Psychiatry. 2012 Jan; 51(1): 86–97.e8. This meta-analysis of 24 published studies on food colors, plus 10 more on dietary restriction, concluded that a restriction diet (e.g., the Feingold diet or an … Continue reading
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Pediatric Nursing. 2007 Mar-Apr; 33(2): 138-43. This review is intended to help nurses support parents who want to try various therapeutic diets such as the Feingold diet, oligoantigenic (few foods) diet, or gluten-free, casein-free diet for their children. The nurses … Continue reading
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Journal of Paediatrics and Child Health. 1997 June; 33(3): 190-4. The author summarizes and discusses the research from the 1970s up until the 1990s. She emphasizes that studies often only can deal with a single item but in actuality there … Continue reading
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Applied Psychophysiology and Biofeedback, 2003 March; 28(1): 63-75. In this paper, Schnoll reviews the research on food additives, refined sugars, food allergies, and fatty acid metabolism as it relates to ADHD. QUOTE: “Although clinicians and researchers alike acknowledge the complex … Continue reading
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Roczniki Panstwowego Zakladu Higieny. 2012;63(2): 127-34 In this review of ADHD treatments, Konikowska describes hyperactivity as a genetic trait connected to abnormal brain maturation, likely related to less activity by neurotransmitters dopamine and norepinephrine. While stimulant medications effectively increase the … Continue reading
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Journal of Allergy and Clinical Immunology, 2000 Mar;105(3):462-7 In this study, a questionnaire was filled out by 366 adult asthma patients. Over 33% of them said that their asthma had been triggered by alcohol at least twice, with wine reported … Continue reading
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Prenatal Diagnosis. 2016, Sep 29. doi: 10.1002/pd.4932 Edlow reviews the current animal and human research showing a connection between maternal (and sometimes paternal) obesity and high fat diets on neuro-developmental and psychiatric disorders in the offspring. These disorders include cognitive … Continue reading
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Annual Review of Public Health, 2015 Mar 18;36:211-30. The objective of this review is to provide an overview on the population impact of toxins on the developing brain and describe implications for public health. QUOTE: “The blood–brain barrier of the … Continue reading
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Annals of Allergy 1977 Jul;39(1):28-37 This is an early review of the combination of asthma, nasal pathology and intolerance to aspirin as a “unique syndrome” with a tendency for diabetes as well as a prolongation of bleeding time. Abrishami mentions … Continue reading
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International Journal of Nursing Studies, 2005 Feb;42(2):229-41 In this review, it is noted that deficiencies in cholesterol, tryptophan (an amino acid), protein, iron, or zinc are each connected to an increase in aggression as well as cognitive and behavior problems. … Continue reading
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Pharmacological Research, 1999. Sep;40 (3):211-25 DHA and EPA are long-chain omega-3 fatty acids. This review lists the many benefits of these as well as the effects of a deficiency in both infants and adults. QUOTE: “… deficiencies of DHA are … Continue reading
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Alternative Therapies in Health and Medicine, 2015. 21 Suppl 1:52-62. During the past 50 years, the amount of synthetic dye used in foods has increased by 500%. At the same time, there has been an alarming rise in behavioral problems … Continue reading
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Acta Alimentaria, 43(2), 344-359. QUOTE: “Given that it is now well-known that autistic patients tend to be PST-deficient, causal link between a low-salicylate diet and the mitigation of symptom-severity seems a rather plausible hypothesis.” QUOTE: “It is quite apparent from … Continue reading
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Journal of Child Psychology & Psychiatry, 2014 May;55(5):416-27. The author compares 3 kinds of studies for treatment of ADHD – restricted elimination diets (RED), artificial food colour elimination (AFCE), and essential fatty acid (e.g. fish oil) supplements (SFFA). He concludes … Continue reading
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European Child & Adolescent Psychiatry, 2014 Jul;23(7):519-29. Verlaet discusses the common causes of GI problems, asthma, eczema, ear infections, and ADHD – involving both genes, immunity, and inflammation. An immune imbalance can be related to food provoking ADHD-like behavior. Food … Continue reading
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The Medical Journal of Australia, 2013. Jun 17; 198(11): 600-2. Gray was treating patients who had tried the low-salicylate diet (called the FAILSAFE diet) used in Australia, which is more restrictive than the Feingold diet, eliminating both more of the … Continue reading
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JMED Research, Vol. 2013 (2013) This is a review of the studies about MSG and its influence on different systems in humans. Effects of injected MSG into rats included neuron damage, and prefrontal cerebral cortex changes, but such tests cannot … Continue reading
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American Journal of Psychiatry, 2013. March. 170(3): 275-89. This paper is a review of dietary and psychological treatments for ADHD. QUOTE (Conclusion): “Free fatty acid supplementation and artificial food color exclusions appear to have beneficial effects on ADHD symptoms, although … Continue reading
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Nutrition Review, 2013 May;71(5):268-81. Stevens reviews the research on mechanisms by which food dyes and common foods may cause behavioral changes in children with and without ADHD. The three potential mechanisms are toxicological, antinutritional, and hypersensitivity. Suggestions for future studies … Continue reading
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Frontiers in Human Neuroscience, 2013 Jan 4;6:344. This is a review of evidence suggesting that a gluten-free diet, a casein-free diet (or both) are helpful for people on the autism spectrum. QUOTE: “Although not wholly affirmative, the majority of published … Continue reading
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Neurotherapeutics. 2012 Jul;9(3):599-609. Arnold reviews the history of the effects of artificial food colors (AFC) on ADHD and the testimony to the 2011 FDA Food Advisory Committee. Arnold discusses possible biological mechanisms such as the effects of food dyes on … Continue reading
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Pediatrics, 2012 Feb;129(2): 330-7. Millichap says his article is a comprehensive overview of the role of diet for treatment of children with ADHD “when pharmacotherapy has proven unsatisfactory or unacceptable.” He promises to talk about new research. Unfortunately, he falls … Continue reading
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Environmental Health Perspectives, 2012 Jan;120(1):1-5. Dr. Weiss examines the basis of the FDA’s position on food dyes, the decision of the Food Advisory Committee, and the reasons that this is an environmental health issue He points out that they limited … Continue reading
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European Child & Adolescent Psychiatry, 2011. 20 (9), 431-2. Concerned about the enormous increase in use of psychostimulant drugs such as Ritalin, the authors of this editorial discuss the research supporting the use of other options. In particular, they find … Continue reading
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Clinical Pediatrics (Phila), 2011. Apr; 50(4): 279-93. In their review of the literature, Stevens et al conclude that the evidence indicates that a diet free of food dyes is appropriate for “children who have not responded satisfactorily to conventional treatment, … Continue reading
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Journal of Alternative and Complementary Medicine, 2008. Jan-Feb; 14(1): 79-85. This is a review of literature available in 2008. The authors say many of the studies link exposure to toxins such as mercury, lead, and pesticides, as well as prenatal … Continue reading
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Prescrire International, 2009. Oct; 18(103): 215 (no author listed) In a health assessment of artificial food dyes, Prescrire International, a non-profit organization providing information and continuing education for healthcare professionals, considers the hypothesis that artificial food dyes worsen hyperactivity symptoms … Continue reading
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Journal of Developmental and Behavioral Pediatrics, 2004 Dec;25(6):423-34. Searching 10 databases for double-blind placebo-controlled trials on the effects of artificial food dyes, Schab and Trinh found 15 that met their criteria. QUOTE: “Our meta-analysis supports the hypothesis that AFCs (artificial … Continue reading
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Journal of Applied Nutrition, November 1, 1991, Vol. 43. In a review of diet changes made in 813 prisons in California, implementation of “nutrient dense diets” resulted in “significantly improved conduct, intelligence, and/or academic performance” Full Text || Get Password
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Nutrition and Health. 1984; 3(1-2): 39-54. Menzies reviews the existing literature and presents a number of case studies of children with idiosyncratic responses to foods and additives. QUOTE: “Perhaps not enough attention has been paid to the role of biological … Continue reading
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Journal of Learning Disabilities, 1983. Jun-Jul;16(6):319-23. Mattes gives his opinion that improvement on the Feingold diet is “based on anecdotal evidence;” he claims that the studies show the diet “is probably not effective, except perhaps in a very small percentage … Continue reading
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Ecology of Disease, 1982. 1(2-3):153-65 QUOTE: The increase in behavioural disorders accompanied by a persistent drop in scholastic performance coupled with the continuing rise in the prevalence of delinquency is undoubtedly one of the most important expressions of the disruption … Continue reading
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Mattes & Gittelman, Archives of General Psychiatry. 1981. June; 38(6): 714-8 Mattes claimed he tried to maximize the behavioral effects of artificial food dyes by (1) studying only children already on the Feingold diet, (2) trying to exclude placebo responders, … Continue reading
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International Journal of Offender Therapy and Comparative Criminology, 1979. Vol 23(1) 73-84. QUOTE: “This disenchantment with present-day rehabilitation techniques prompted the Ford Foundation in its annual report for 1977 to recommend that the role in delinquency of biochemical and organic … Continue reading
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Journal of the American Society for Preventive Dentistry, 1977 Jan-Feb;7(1):13-5. QUOTE: “The presence of food additives in products used in dental procedures may have serious consequences for many patients. Hyperactivity and learning disabilities as well as buccal, gingival and … Continue reading
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Speech to American Academy of Pediatrics, New York Hilton Hotel, November 8, 1977. QUOTE: ”Recognizing that any compound under the appropriate conditions can induce adverse reactions, including behavioral disturbances, it becomes necessary to evaluate each compound or class of compounds … Continue reading
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Journal of Learning Disabilities, 1976. Vol.9(9) pp.19-27 Dr. Feingold reviews the historical background of hyperkinesis (hyperactivity) and learning disabilities, and discusses the food additives. He explains the importance of artificial food dyes and flavors. MedLine || Full Text
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Journal of Learning Disabilities, November 1976 vol.9 no.9 p.560-569 Spring reviewed the few studies available at that time and concluded that there was no “epidemic” of hyperactivity in the 1970s because a particular WISC reading score average was higher in … Continue reading
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The American Journal of Nursing, 1975 May;75(5):797-803. QUOTE: “… It is important to recognize that this entire behavioral pattern is beyond the child’s voluntary control. He does not choose to be a failure nor does he want to be bad. … Continue reading
