Author Archives: Shula

Lau 2006: Synergistic Interactions Between Commonly Used Food Additives in a Developmental Neurotoxicity Test

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Toxicological Sciences. 2006 Mar; 90(1):178-87. This is one of the few studies examining and comparing the neurotoxic activity of food additives alone and in combination.   After determining how much of each additive reduces neurite development by 20%, Lau combined pairs … Continue reading

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Lien 2006: Consumption of soft drinks and hyperactivity, mental distress, and conduct problems among adolescents in Oslo, Norway

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American Journal of Public Health, 2006. Oct;96(10):1815-20 The authors surveyed almost 5,500 students in 10th grade to see how many sugar-containing soft drinks they consumed per day and to assess their mental health and conduct. AUTHORS’ CONCLUSIONS:  “High consumption levels … Continue reading

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Niederhofer 2006: A preliminary investigation of ADHD symptoms in persons with celiac disease

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Journal of Attention Disorders, 2006. Nov;10(2):200-4. Because several studies had reported a possible association of celiac disease (CD) and ADHD symptoms, the authors evaluated 132 participants diagnosed with CD – both children and adults – for ADHD symptoms before they … Continue reading

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Bateman 2004: The effects of a double blind, placebo controlled, artificial food colourings and benzoate preservative challenge on hyperactivity in a general population sample of preschool children

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Archives of Disease in Childhood. 2004 Jun;89(6):506-11. The authors put 277  3-year-old children from the general population on a diet without artificial food dyes or benzoate preservatives for a week, and then challenged them at various times with a drink … Continue reading

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Schab 2004: Do artificial food colors promote hyperactivity in children with hyperactive syndromes? A meta-analysis of double-blind placebo-controlled trials

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Journal of Developmental and Behavioral Pediatrics, 2004 Dec;25(6):423-34. Searching 10 databases for double-blind placebo-controlled trials on the effects of artificial food dyes, Schab and Trinh found 15 that met their criteria. QUOTE:  “Our meta-analysis supports the hypothesis that AFCs (artificial … Continue reading

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Dengate 2002: Controlled trial of cumulative behavioural effects of a common bread preservative

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Journal of Paediatrics and Child Health, 2002. Aug;38(4):373-6 In Australia, 27 children whose behavior had improved on the Royal Prince Alfred Hospital diet were enrolled in a double-blind placebo-controlled test of the bread preservative calcium propionate (preservative code 282).  More … Continue reading

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Pelsser 2002: Favourable effect of a standard elimination diet on the behavior of young children with attention deficit hyperactivity disorder (ADHD): a pilot study

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Nederlandsch tijdschrift voor geneeskunde 2002, Dec 28;146(52):2543-7. 36 boys and 4 girls, diagnosed with ADHD, were put on an oligoantigenic (few foods – rice, turkey, pear and lettuce) diet for two weeks.  9 children (23%) withdrew from the study because of … Continue reading

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Bennett 1998 The Shipley Project: Treating Food Allergy to Prevent Criminal Behaviour in Community Settings

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Journal of Nutritional & Environmental Medicine , Vol.8, No.1, Mar.1998, pp.77-83 All 9 children with disruptive and/or criminal behavior in this study were found to have a number of food allergies or intolerances and mineral imbalances, particularly zinc. Three also … Continue reading

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Update

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For those who may be wondering about the lack of newly posted studies on here over the past few weeks, I just want to let you know I did not drop out of sight …. exactly.  I have found a … Continue reading

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Starobrat-Hermelin 1998:   The effect of deficiency of selected bioelements on hyperactivity in children with certain specified mental disorders

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Annales Academiae Medicae Stetinensis, 1998;44:297-314 Deficiencies of magnesium, copper, zinc, calcium, and iron occur more in children with ADHD, and magnesium deficiency is the most frequent.   Starobrat-Hermelin studied a group of 110 hyperactive children who also had a variety … Continue reading

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Bennett 1997: The Health of Criminals Related to Behaviour, Food, Allergy and Nutrition: A Controlled Study of 100 Persistent Young Offenders

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Journal of Nutritional & Environmental Medicine, Vol.7, No.4 Dec 1997 pp.359-366 About 75% of persistent young offenders have behaviors linked to food sensitivity and nutrition problems; only 18% of young non-offenders have such problems. MedLine || Full Text || Get Password

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Schmidt 1997: Does oligoantigenic diet influence hyperactive/conduct-disordered children–a controlled trial

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European Child & Adolescent Psychiatry, 1997. Jun;6(2):88-95. Fig. 1 Study design Schmidt compared the effectiveness of an oligoantigenic (few foods) diet with Ritalin for hyperactive disruptive children (today called conduct disorder).   44% responded to Ritalin while 24% responded equally well … Continue reading

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Uhlig 1997: Topographic mapping of brain electrical activity in children with food-induced attention deficit hyperkinetic disorder

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European Journal of Pediatrics, 1997. Jul;156(7):557-61. Uhlig carried out EEG brain mapping on 15 children with food-induced ADHD, both when they were on their diet and when they had been given provoking foods. Consuming the provoking foods caused a significant … Continue reading

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Reyes 1996: Effect of organic synthetic food colours on mitochondrial respiration

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Food Additives and Contaminants, 1996. Jan;13(1):5-11 In this lab study, 11 artificial food dyes – not all of them used in the US — were tested to determine their effect on the mitochondria of rat liver and kidney. NOTE:  Mitochondria … Continue reading

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Boris 1994: Foods and Additives are Common Causes of the Attention Deficit Hyperactive Disorder in Children

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Annals of Allergy, May 1994, Vol. 72, pp. 462-8. 73% of 26 children with ADHD responded favorably to a diet eliminating reactive foods and artificial colors. 16 of the improved children were given a double blind challenge with 100 mg … Continue reading

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Rowe 1994: Synthetic Food Coloring and Behavior: A Dose Response Effect in a Double-Blind, Placebo-Controlled, Repeated-Measures Study

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Journal of Pediatrics, November 1994, Vol. 135, pp.691-8 150 of 200 children [75%] improved on an open trial of a diet free of synthetic food coloring, and deteriorated upon introduction of foods containing synthetic colorings. 34 other “clear” or “suspected” … Continue reading

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Carter 1993: Effects of a Few Foods Diet in Attention Deficit Disorder

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Archives of Disease in Childhood, November 1993, Vol. 69 (5), pp.564-8 59 of 78 children (75.6%) referred for “hyperactive behavior” improved on an open trial of an elimination diet.  19 of them were studied in a placebo-controlled double-blind challenge protocol. … Continue reading

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Egger 1992: Effect of diet treatment on enuresis in children with migraine or hyperkinetic behavior

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Clinical Pediatrics (Phila) 1992 May;31(5):302-7. 21 children with migraine and/or hyperkinetic behavior disorder also had daytime or nighttime enuresis (wetting).  Use of an oligoantigenic (few-foods) diet controlled their migraine and/or hyperkinesis, and for 76% of them the diet also stopped … Continue reading

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Novembre 1992: Unusual reactions to food additives

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Pediatria Medica e Chirurgica 1992 Jan-Feb;14(1):39-42 The author describes two cases of reactions to the food additives tartrazine (Yellow 5) and benzoates involving mainly the central nervous system (headache, migraine, overactivity, concentration and learning difficulties, depression) and joints (arthralgias), confirmed … Continue reading

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Schoenthaler 1991: Applied Nutrition and Behavior

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Journal of Applied Nutrition, November 1, 1991, Vol. 43. In a review of diet changes made in 813 prisons in California, implementation of “nutrient dense diets” resulted in “significantly improved conduct, intelligence, and/or academic performance” Full Text || Get Password

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Pollock 1990: Effect of artificial food colours on childhood behaviour

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Pollock & Warner, Archives of Disease in Childhood, 1990.  Jan;65(1):74-7, Heart and Lung Institute, Brompton Hospital, London. Pollock did a double-blind placebo-controlled challenge study on 19 children who had improved previously on an additive-free diet.   He didn’t use any additives … Continue reading

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Sarantinos 1990: Synthetic Food Colouring and Behavioural Change in Children with Attention Deficit Disorder: A Double-Blind, Placebo Controlled, Repeated Measures Study

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Proceedings of the Nutrition Society of Australia, 1990 pg. 233. Sarantinos studied 13 children,  4-14 years old, who had been at least 6 weeks on a diet free of synthetic food dyes as part of their treatment for ADHD.  The … Continue reading

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Ward 1990: The influence of the chemical additive tartrazine on the zinc status of hyperactive children: A double-blind placebo-controlled study

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Journal of Nutritional Medicine; 1 (1). 1990. 51-58. Ward first studied the zinc status in various tissues (blood, hair, saliva, etc) in 20 hyperactive boys compared to 20 non-hyperactive boys.  Then, in a double-blind placebo-controlled study of 10 hyperactive boys … Continue reading

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Egger 1989: Oligoantigenic diet treatment of children with epilepsy and migraine

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Journal of Pediatrics, 1989. Jan;114(1):51-8. Egger put 45 children with epilepsy and recurrent headaches, abdominal symptoms, or hyperactivity on an oligoantigenic (few foods) diet.   36 of them — 80% — improved. QUOTE:  “Headaches, abdominal pains, and hyperkinetic behavior ceased … Continue reading

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Kaplan 1989: Overall Nutrient Intake of Preschool Hyperactive and Normal Boys

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Journal of Abnormal Child Psychology, April 1989, Vol. 17(2), pp.127-32. Kaplan compared food diaries of children with and without ADHD and concluded that it was idiosyncratic sensitivities to components in the diet rather than a different overall diet. MedLine || … Continue reading

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Rowe 1988: Synthetic Food Colourings and “Hyperactivity”: a Double-Blind Crossover Study

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Australian Paediatric Journal, April 1988, Vol. 24 (2), pp. 143-7 Of 220 children referred for suspected hyperactivity, 55 were put on a 6-week trial of the Feingold Diet.    40 of them — 72.7% — exhibited improved behavior, and 26 of … Continue reading

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Burlton-Bennett 1987: A Single Subject Evaluation of the K-P Diet for Hyperkinesis

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Journal of Learning Disabilities, 1987 Jun-Jul;20(6):331-5, 346. A single subject ABAB (on-off-on-off) design was used to test the effectiveness of the Feingold (K-P) diet in the treatment of a 6-year-old hyperkinetic male who seemed to  be diet-responsive.  His behavior was … Continue reading

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David 1987: Reactions to dietary tartrazine

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Archives of Disease in Childhood, 1987. Feb;62(2):119-22. In a double-blind study, David challenged 24 of his patients who had been using diet for ADHD with benzoic acid (a preservative) and a large dose of coloring — 250 mg of Yellow … Continue reading

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Gross 1987: The effect of diets rich in and free from additives on the behavior of children with hyperkinetic and learning disorders

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Journal of the American Academy of Child and Adolescent Psychiatry. 1987. Jan;26(1):53-5. Gross carried out a diet study in a summer camp which is a great way to totally control the diet and get solid results in a study. NOTE:  … Continue reading

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Schoenthaler 1986: The Impact of a Low Food Additive and Sucrose Diet on Academic Performance in 803 New York City Public Schools

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International Journal for Biosocial Research, 1986, 8(2); 185-195. Over 4 years, 803 New York City schools changed their breakfast and lunch programs.  They lowered sucrose, synthetic food color/flavors, and two preservatives (BHA and BHT). For each change, there was an … Continue reading

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Egger 1985: Controlled Trial of Oligoantigenic Treatment in the Hyperkinetic Syndrome

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The Lancet, 9;1(8428):540-5. 62 of 76  (81.6%) overactive children improved by at least one grade level on an oligoantigenic (few foods) diet.  Benzoic acid and tartrazine (Yellow 5) were the most common problems, but all children had other sensitivities as … Continue reading

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Menzies 1984: Disturbed children: the role of food and chemical sensitivities

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Nutrition and Health. 1984; 3(1-2): 39-54. Menzies reviews the existing literature and presents a number of case studies of children with idiosyncratic responses to foods and additives. QUOTE:  “Perhaps not enough attention has been paid to the role of biological … Continue reading

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Egger 1983: Is migraine food allergy? A double-blind controlled trial of oligoantigenic diet treatment

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Lancet, 1983. Oct 15;2(8355):865-9 93% of 88 children with severe frequent migraine recovered on an oligoantigenic (few foods) diet.  40 of them were challenged with various foods in a double-blind test, establishing that it was the diet that had helped.  … Continue reading

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Mattes 1983: The Feingold diet: a current reappraisal

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Journal of Learning Disabilities, 1983.  Jun-Jul;16(6):319-23. Mattes gives his opinion that improvement on the Feingold diet is  “based on anecdotal evidence;” he claims that the studies show the diet “is probably not effective, except perhaps in a very small percentage … Continue reading

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Feingold 1982: The role of diet in behaviour

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Ecology of Disease, 1982. 1(2-3):153-65 QUOTE:   The increase in behavioural disorders accompanied by a persistent drop in scholastic performance coupled with the continuing rise in the prevalence of delinquency is undoubtedly one of the most important expressions of the disruption … Continue reading

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Goldenring 1982: Sulfanilic acid: behavioral change related to azo food dyes in developing rats

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Neurobehavioral Toxicology and Teratology, 1982. Jan-Feb;4(1): 43-9. Goldenring studied the effects of giving sulfanilic acid to rat pups.  He chose this chemical because it is formed when azo food dyes are digested.  He gave the sulfanilic acid to normal rat … Continue reading

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Salamy 1982: Physiological changes in hyperactive children following the ingestion of food additives

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International Journal of Neuroscience, 1982. May;16(3-4):241-246 QUOTE:  “… The physiological measures [EEG and heart rate] were obtained prior to and following the ingestion of drinks containing food additives or placebos, which were administered in a double-blind, randomized, crossover procedure. … … Continue reading

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Mattes 1981: Effects of artificial food colorings in children with hyperactive symptoms. A critical review and results of a controlled study

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Mattes & Gittelman, Archives of General Psychiatry. 1981. June; 38(6): 714-8 Mattes claimed he tried to maximize the behavioral effects of artificial food dyes by (1) studying only children already on the Feingold diet,  (2) trying to exclude placebo responders, … Continue reading

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Swanson 1980: Food Dyes Impair Performance of Hyperactive Children on a Laboratory Learning Test

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Science, March 28, 1980, Vol. 207. pp.1485-7 QUOTE:  “The performance of the hyperactive children on paired-associate learning tests on the day they received the dye blend was impaired relative to their performance after they received the placebo, but the performance … Continue reading

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Weiss 1980: Behavioral responses to artificial food colors

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Science, 1980. March 28;207 (4438): 1487-9. QUOTE:  ”Twenty-two young children, maintained on a diet that excluded certain foods, were challenged intermittently with a blend of seven artificial colors in a double-blind trial. Parents’ observations provided the criteria of response. One … Continue reading

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Brenner 1979: Trace mineral levels in hyperactive children responding to the Feingold diet

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The Journal of Pediatrics. 1979. June; 94(6):944-5 Trying to find a reason why some children respond well to the Feingold Diet and others don’t, Brenner measured copper and zinc levels in the blood of 20 children who had responded well … Continue reading

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Feingold 1979: Dietary management of juvenile delinquency

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International Journal of Offender Therapy and Comparative Criminology, 1979. Vol 23(1) 73-84. QUOTE:  “This disenchantment with present-day rehabilitation techniques prompted the Ford Foundation in its annual report for 1977 to recommend that the role in delinquency of biochemical and organic … Continue reading

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Lafferman 1979: Erythrosin B inhibits dopamine transport in rat caudate synaptosomes.

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Science. 1979. July 27; 205 (4404): 410-2. Lafferman found that erythrosin B [Red 3] given to rats prevents the uptake of dopamine (the “feel good” neurotransmitter) by nerve cells in the brain called the caudate synaptosomes.  This is consistent with … Continue reading

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Shaywitz 1979: Effects of chronic administration of food colorings on activity levels and cognitive performance in developing rat pups treated with 6-hydroxydopamine

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Neurobehavioral Toxicology, 1979.  Spring;1(1):41-7.  (Today called Neurotoxicology and Teratology) In a study on rat pups, the highest dose of food dyes caused the greatest activity.  Even after a half hour, the pups only calmed down by 7.25% — while the … Continue reading

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Dumbrell 1978: Is the Australian version of the Feingold diet safe?

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Medical Journal of Australia, 1978 Dec 2;2(12):548, 569-70. The Feingold diet, as used in Australia, was found to be nutritionally superior to a “normal” diet, and pronounced safe to use. MedLine

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Fitzsimon 1978: Salicylate sensitivity in children reported to respond to salicylate exclusion

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Medical Journal of Australia, 1978. Dec 2;2(12):570-2 To test for reactions to salicylate, 12 children who had been on the Feingold diet for about a year were challenge-tested with 40 mg of acetylsalicylic acid (aspirin) in a double-blind, cross-over trial … Continue reading

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Goyette 1978: Effects of artificial colors on hyperkinetic children: a double-blind challenge study

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Psychopharmacology Bulletin, 1978. April;  14(2):39-40 Goyette performed two studies: Experiment One:  16 children were put on the diet and were much improved according to both parents and teachers.  Then they were challenged with two cookies per day (with or without … Continue reading

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Harley 1978: Hyperkinesis and food additives: testing the Feingold hypothesis

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Pediatrics, 1978. Jun;61(6):818-28 In a double-blind diet study in which all food was provided for a “Feingold Diet” and a “control diet,” parents of 63% of the 36 school-age children and 100% of the 10 preschool children reported improved behavior … Continue reading

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Harper 1978: Nutrient intakes of children on the hyperkinesis diet

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Journal of the American Dietetic Association, 1978 Nov;73(5):515-9 Harper calculated the nutrient intake of 54 children before and on the Feingold diet.   They were as good or better than the Recommended Dietary Allowances (RDA) — in other words, the … Continue reading

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Hindle 1978: The management of hyperkinetic children: a trial of dietary therapy

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New Zealand Medical Journal, 1978. Jul 26;88(616):43-5. QUOTE:  “Ten hyperkinetic children have been treated with the [Feingold] diet, five of whom improved dramatically and are now off all other therapy. Their response to accidental and deliberate challenge supports the hypothesis … Continue reading

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Levy 1978: Hyperkinesis and diet: a double-blind crossover trial with a tartrazine challenge

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Medical Journal of Australia, 1978. Jan 28;1(2):61-4 In this double-blind study of 22 hyperactive children, Levy put them on an elimination diet for four weeks and then challenged them with Yellow 5.  She reported that their improvement in the first … Continue reading

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Rose 1978: The functional relationship between artificial food colors and hyperactivity.

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Journal of Applied Behavior Analysis 1978 Winter; 11(4):439-46 This was a double-blind study on two girls who had been on the Feingold diet for almost a year. Trained observers watched them in school and reported on the frequency of the … Continue reading

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Williams 1978: Relative effects of drugs and diet on hyperactive behaviors: an experimental study

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Pediatrics. 1978 Jun;61(6):811-7. 26 hyperactive children were given a “modified” Feingold diet in which artificial food dyes and flavorings were eliminated, but not preservatives or salicylates.    They were then challenged in four ways: Cookie with 13 mg food dyes + … Continue reading

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Brenner 1977: A study of the efficacy of the Feingold diet on hyperkinetic children. Some favorable personal observations.

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Clinical Pediatrics (Phila) 1977 Jul;16(7):652-6 (Case studies) When 32 hyperactive children Dr. Brenner had been treating medically for years were given the Feingold diet, 11 of them — 34.3% —  “markedly improved.“  Another 2 improved as much but were older, … Continue reading

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Feingold 1977: Food additives in dentistry

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Journal of the American Society for Preventive Dentistry, 1977 Jan-Feb;7(1):13-5. QUOTE:   “The presence of food additives in products used in dental procedures may have serious consequences for many patients. Hyperactivity and learning disabilities as well as buccal, gingival and … Continue reading

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Feingold 1977: Hyperkinesis and Learning Disabilities Linked to the Ingestion of Artificial Food Colors and Flavors

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Speech to American Academy of Pediatrics, New York Hilton Hotel, November 8, 1977. QUOTE:  ”Recognizing that any compound under the appropriate conditions can induce adverse reactions, including behavioral disturbances, it becomes necessary to evaluate each compound or class of compounds … Continue reading

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Conners 1976: Food additives and hyperkinesis: a controlled double-blind experiment

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Pediatrics,  1976 Aug;58(2):154-66. In a double-blind crossover study, 15 children were given a control diet and the “K-P” (Feingold) diet eliminating artificial flavors, colors, and natural salicylates. QUOTE:  “Both parents and teachers reported fewer hyperkinetic symptoms on the K-P diet … Continue reading

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Cook 1976: The Feingold dietary treatment of the hyperkinetic syndrome

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Medical Journal of Australia. 1976 Jul 17;2(3):85-8, 90. In Australia, 15 children were given the Feingold diet.  Parents of 13 of them (87%) reported improvement in their children’s behaviour and a relapse upon eating off-diet items. MedLine

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Feingold 1976: Hyperkinesis and Learning Disabilities Linked to the Ingestion of Artificial Food Colors and Flavors

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Journal of Learning Disabilities, 1976. Vol.9(9) pp.19-27 Dr. Feingold reviews the historical background of hyperkinesis (hyperactivity) and learning disabilities, and discusses the food additives.   He explains the importance of artificial food dyes and flavors. MedLine || Full Text

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Salzman 1976: Allergy testing, psychological assessment and dietary treatment of the hyperactive child syndrome

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Medical Journal of Australia 1976 Aug 14;2(7):248-51 Thirty-one children with behavioural problems and learning difficulties were allergy tested … 15 of them were given the Feingold diet (then called the KP Diet).  Ninety-three per cent (93%) responded with improved behaviour … Continue reading

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